Intra-abdominal View and Inflammatory Markers in Secondary Peritonitis - Correlation to Recovery
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 283
- Locations
- 1
- Primary Endpoint
- Mortality
Study Overview
Brief Summary
The purpose of this study is to analyze the correlation between intra-abdominal view and patient recovery in secondary peritonitis, and to create a new classification based on these results. Additionally, a variety of inflammatory markers from blood samples will be collected in order to analyze their correlation with patient outcomes.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •adult patients > 18 years old
- •operated for complicated intra-abdominal infection
Exclusion Criteria
- •another diagnosis requiring ICU level care at the same time
- •acute pancreatitis
- •acute mesenteric ischaemia due to occlusion in superior mesenteric artery or vein
- •peritonitis due to timely diagnosed trauma
- •missing informed consent or inability to understand it
Outcomes
Primary Outcomes
Mortality
Time Frame: 90 days
Death within 90 days of primary operation for diffuse peritonitis
ICU admission
Time Frame: 90 days
Intensive Care Unit admission and length of ICU treatment
Reoperations
Time Frame: 90 days
Reoperations needed postoperatively
Complications
Time Frame: 90 days
Postoperative complications according to Clavien-Dindo classification
Length of hospitalization
Time Frame: 90 days
Days in hospital postoperatively
Secondary Outcomes
No secondary outcomes reported
Investigators
Matti Tolonen
M.D.
Helsinki University Central Hospital