Intra-abdominal View and Inflammatory Markers in Secondary Peritonitis - Correlation to Recovery

Completed

• Conditions: Peritonitis

• Registration Number: NCT02726932
• Lead Sponsor: Helsinki University Central Hospital

Brief Summary

The purpose of this study is to analyze the correlation between intra-abdominal view and patient recovery in secondary peritonitis, and to create a new classification based on these results. Additionally, a variety of inflammatory markers from blood samples will be collected in order to analyze their correlation with patient outcomes.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2016-03-29
• Study First Submitted QC: 2016-03-29
• Study Start: 2016-03-30
• Study First Posted: 2016-04-04
• Primary Completion: 2018-03-30
• Study Completion: 2018-03-30
• Status Verified: 2019-01
• Last Update Submitted: 2019-01-15
• Last Update Posted: 2019-01-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 283

Inclusion Criteria

• adult patients > 18 years old
• operated for complicated intra-abdominal infection

Exclusion Criteria

• another diagnosis requiring ICU level care at the same time
• acute pancreatitis
• acute mesenteric ischaemia due to occlusion in superior mesenteric artery or vein
• peritonitis due to timely diagnosed trauma
• missing informed consent or inability to understand it

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mortality	90 days	Death within 90 days of primary operation for diffuse peritonitis
ICU admission	90 days	Intensive Care Unit admission and length of ICU treatment
Reoperations	90 days	Reoperations needed postoperatively
Complications	90 days	Postoperative complications according to Clavien-Dindo classification
Length of hospitalization	90 days	Days in hospital postoperatively

Trial Locations

Locations (1)

Helsinki University Central Hospital; 🇫🇮 Helsinki, Finland