Assessment the Role of Tranexamic Acid in Prevention of Postpartum Hemorrhage”

Not Applicable

Completed

• Conditions: Haematological Disorders; Pregnancy and Childbirth; postpartum hemorrhage; Anaesthesia

• Registration Number: PACTR202102576748863
• Lead Sponsor: Faculty of medicine Ain Shams University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-02-05
• Last Update Posted: 2023-05-29

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

Singleton pregnancy, P1-CS (previous one section after failed consent for trial of labor after CS), Term = 37 weeks of gestation , Elective cesarean section, spinal anesthesia and written Informed consent.

Exclusion Criteria

Failed spinal anesthesia (more than 2 attempts), Multiple pregnancy, Grand multipara, Placenta previa, Abruptio placentae, Polyhydraminos, Fever, Rupture of membranes, Patients on anticoagulants or antiplatelets, History of eclampsia or pre-eclampsia in current pregnancy, History of cardiovascular complications as Coronary artery disease or myocardial infarction, Repaired or unrepaired congenital heart disease, unstable arrhythmia or Congestive heart failure, or the patient had a contraindication to TXA administration as history of venous thromboembolism, active thromboembolic disease, high risk of thrombosis (e.g. factor V Leiden or protein C deficiency), allergy to TXA, Pre-existing hematuria or history of renal insufficiency

Study & Design

• Study Type: Interventional
• Study Design: Not specified