Use of MgSO4 for Pain After Bariatric Surgery

Not Applicable

Completed

• Conditions: Therapeutic Opioid Induced Constipation (Disorder)
• Interventions: Drug: Magnesium

• Registration Number: NCT03355807
• Lead Sponsor: Yeditepe University Hospital

Brief Summary

The purpose of this study was to investigate the effect of magnesium sulfate on pain management for pain after sleeve gastrectomy operation

Detailed Description

The purpose of this study is to investigate the effect of magnesium sulfate on pain management for pain after sleeve gastrectomy operation.

Design: A prospective, randomized, controlled clinical study.

Setting: University hospital.

Participants: Eighty patients undergoing sleeve gastrectomy.

Measurements and Main Results: Visual analog scale for pain score, sedation score, mean arterial pressure, heart rate, and valid and invalid analgesic demand will record. Serum magnesium levels will determined at preoperative evaluation, postanesthesia care unit admission and at 24 hours. Side effects will also record.

Study Timeline

• Study Start: 2017-01-01
• Study First Submitted: 2017-09-28
• Study First Submitted QC: 2017-11-27
• Study First Posted: 2017-11-28
• Primary Completion: 2017-12-15
• Study Completion: 2017-12-15
• Status Verified: 2018-05
• Last Update Submitted: 2018-05-21
• Last Update Posted: 2018-05-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• 18 to 65 year old individuals who underwent laparoscopic sleeve gastrectomy.

Exclusion Criteria

• One or more of the following: cardio - vascular and respiratory diseases, drug and/or alcohol abuse, use of daily an algesia 24 hours before the surgery, renal failure, and liver dysfunction.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group MgSO4	Magnesium	The magnesium group (group Mg, n _ 40) received an additional infusion of MgSO4 (30 mg/kg by bolus and 10 mg/kg/h by infusion for 24 hours)

Primary Outcome Measures

Name	Time	Method
Item pain intensity measure assessed by using VAS scores	1 day	Pain was assessed by using VAS scores (0: no pain and 10: worst pain) imaginable recorded at 0, 1, 2, 4, 6, 24, and 24 hours.