Effect of Hyaluronic Acid on success of Intrauterine Insemination Treatment
Not Applicable
- Registration Number
- CTRI/2021/10/037064
- Lead Sponsor
- All India Institute of Medical Sciences Jodhpur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Couples unable to conceive after having regular, unprotected sexual intercourse for >12 months.
2. BMI <30 kg/m2
3. Husband Semen Analysis within normal references ranges as per WHO 2010 criteria, within last 6 months.
4. Tubal patency documented by HSG/Laparoscopy.
5 Normal Transvaginal ultrasound to exclude any pelvic structural pathology.
6.Genital TB infection ruled out by TB-PCR /BACTEC.
7. Patient consenting to undergo ovulation induction and Intra-uterine insemination treatment
Exclusion Criteria
Patients not giving consent or not willing to follow up.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the effect of intrauterine instillation of hyaluronic acid enriched media on clinical pregnancy rate in intrauterine insemination treatment.Timepoint: 18 months for recruitment and 6 months for follow up and analysis
- Secondary Outcome Measures
Name Time Method Secondary Objectives- <br/ ><br>1.To assess the effect of intrauterine instillation of hyaluronic acid enriched media on biochemical and ongoing pregnancy rate up to 20 weeks in intrauterine insemination treatment. <br/ ><br>2.To the effect of intrauterine instillation of hyaluronic acid enriched media on miscarriage rate in intrauterine insemination treatment. <br/ ><br>3.To estimate patient discomfort and pain following intrauterine instillation using standard pain scale. <br/ ><br>Timepoint: 18 months for recruitment and 6 months for follow up and analysis