Evaluation of Human Efficacy of SOD Like Super Drink

Not Applicable

Completed

• Conditions: Dermatology

• Registration Number: NCT06322589
• Lead Sponsor: TCI Co., Ltd.

Brief Summary

To assess the efficacy of SOD like Super Drink on anti-oxidant capacity, immuno regulation and skin for human

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2024-02-29
• Study Start: 2024-03-01
• Study First Submitted QC: 2024-03-14
• Study First Posted: 2024-03-21
• Primary Completion: 2024-05-15
• Study Completion: 2024-06-30
• Status Verified: 2024-12
• Last Update Submitted: 2024-12-03
• Last Update Posted: 2024-12-06

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• healthy adults aged between 30-65 years old

Exclusion Criteria

• Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder
• Patients with diseases of the skin, liver, kidney.
• Female who is pregnant or nursing or planning to become pregnant during the course of the study.
• Received facial laser therapy, chemical peeling or UV overexposure (> 3 hr/week) in the past 4 weeks.
• Students who are currently taking courses taught by the principal investigator of this trial.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
the change of Glutathione (GSH) of blood	Change from Baseline GSH at 8 weeks	venous blood was sampled to measure GSH
the change of Superoxide Dismutase (SOD) of blood	Change from Baseline SOD at 8 weeks	venous blood was sampled to measure SOD
the roughness of skin texture	Rating skin roughness from Baseline skin texture at 8 weeks	IRV full-face skin analyzer was utilized to measure skin texture. Units: arbitrary units
the change of skin elasticity	Change from Baseline skin elasticity at 8 weeks	Cutometer® was utilized to measure skin elasticity. Units: arbitrary units
the change of Total Anti-oxidative Capacity (TAC) of blood	Change from Baseline TAC at 8 weeks	venous blood was sampled to measure TAC
the change of Glutathione S-transferase (GST) of blood	Change from Baseline GST at 8 weeks	venous blood was sampled to measure GST
the volume of skin wrinkles	Volume change from Baseline skin wrinkles at 8 weeks	IRV full-face skin analyzer was utilized to measure skin wrinkles. Units: arbitrary units
the change of Malondialdehyde (MDA) of blood	Change from Baseline MDA at 8 weeks	venous blood was sampled to measure MDA
the change of immune-related cytokines of blood	Change from Baseline immune-related cytokines at 8 weeks	venous blood was sampled to measure immune-related cytokines

Secondary Outcome Measures

Name	Time	Method
the change of skin Transepidermal Water Loss (TEWL)	Change from Baseline TEWL at 8 week	Tewameter® TM 300 was utilized to measure TEWL. Units: arbitrary units
the change of skin surface hydration	Change from Baseline skin surface hydration at 8 week	Corneometer® CM 825 was utilized to measure skin surface hydration. Units: arbitrary units
the change of Skin Erythema Index	Change from Baseline skin Erythema Index at 8 week	Mexameter® MX 18was utilized to measure skin Erythema Index. Units: arbitrary units
the change of Skin Melanin Index	Change from Baseline skin Melanin Index at 8 week	Mexameter® MX 18was utilized to measure Melanin Index. Units: arbitrary units

Trial Locations

Locations (1)

China Medical University of department of cosmeceutics; 🇨🇳 Taichung City, Taiwan