Hormonal Levels in Men With Major Depressive Disorder

Withdrawn

• Conditions: Depression

• Registration Number: NCT00429689
• Lead Sponsor: Sheba Medical Center

Brief Summary

Subjects will be 1000 men meeting the following inclusion criteria: 1) male, age 18-65 years; 2) meeting DSM-IV criteria for major depressive disorder within the past one year, with a HAM-D score \>12.

Subjects will be excluded if they exhibit 1) a substance abuse or dependence disorder within the past year; 2) current psychotic symptoms; or 3) a history of bipolar disorder.

Procedure

After informed consent, eligible patients will have blood drawn for serum hormone levels; cortisol, DHEA-S and testosterone or they will provide a salivary sample for measurement of hormone levels.

We will also test hormone level form 1000 healthy males (from blood or saliva) at the same age for comparison.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2007-01-31
• Study First Submitted QC: 2007-01-31
• Study First Posted: 2007-02-01
• Status Verified: 2011-08
• Last Update Submitted: 2011-08-28
• Last Update Posted: 2011-08-30

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: Male
• Target Recruitment: 2000

Inclusion Criteria

• Male
• Major Depression Disorder
• 18-65

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified