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临床试验/CTRI/2025/09/094267
CTRI/2025/09/094267招募中不适用

Evaluating the relative efficacy of photobiomodulation and pharmacotherapeutic agents in the symptomatic management of myogenous temporomandibular disorders

Dr Javvadi Durga Keerthi Mounavica1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年9月15日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
30
试验地点
1
主要终点
Evaluation of pain reduction

研究概览

简要总结

The aim of this study is to compare two different treatment approaches for managing this condition: traditional medications versus a non-invasive therapy known as photobiomodulation. A total of 30 adult patients diagnosed with myogenous TMD at the Department of Oral Medicine and Radiology will participate in the study. These patients have not received any prior treatment, have no history of trauma, and are experiencing their symptoms for the first time.

Participants will be randomly divided into two groups:

·         Group A will receive standard pharmacological treatment including a combination of ibuprofen (400 mg), paracetamol (325 mg), and chlorzoxazone (250 mg). They will be monitored regularly for changes in symptoms.

·         Group B will receive photobiomodulation therapy, which uses a specific type of laser light (1064 nm Nd:YAG) applied at a low intensity (0.6 W/cm²) to muscle trigger points for 60 seconds on alternate days. This method is designed to reduce pain and inflammation at the muscle level.

Both groups will be followed up over the course of one month to observe improvements in symptoms. The main goal of the study is to determine which treatment helps relieve pain more effectively and more quickly.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Outcome Assessor Blinded

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients diagnosed as myogenous Temporomandibular joint disorders based on research diagnostic criteria.

排除标准

  • 1.Previously treated/ ongoing treatment/ any recurrence.
  • 2.History of Macro trauma 3.Patients with Renal impairment and Hepatotoxicity.

结局指标

主要结局

Evaluation of pain reduction

时间窗: Evaluation of pain reduction- baseline, day 0, 2, 4, 6 (postperatively)

次要结局

  • Increase in Mouth Opening(baseline, day-2, day-4, day-6, 1-month, 2-month & 3-month)

研究者

发起方
Dr Javvadi Durga Keerthi Mounavica
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Javvadi Durga Keerthi Mounavica

Vishnu Dental College

研究点 (1)

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