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Clinical Trials/CTRI/2025/09/094267
CTRI/2025/09/094267
Recruiting
Not Applicable

Evaluating the relative efficacy of photobiomodulation and pharmacotherapeutic agents in the symptomatic management of myogenous temporomandibular disorders

Dr Javvadi Durga Keerthi Mounavica1 site in 1 country30 target enrollmentStarted: September 15, 2025Last updated:

Overview

Phase
Not Applicable
Status
Recruiting
Sponsor
Dr Javvadi Durga Keerthi Mounavica
Enrollment
30
Locations
1
Primary Endpoint
Evaluation of pain reduction

Overview

Brief Summary

The aim of this study is to compare two different treatment approaches for managing this condition: traditional medications versus a non-invasive therapy known as photobiomodulation. A total of 30 adult patients diagnosed with myogenous TMD at the Department of Oral Medicine and Radiology will participate in the study. These patients have not received any prior treatment, have no history of trauma, and are experiencing their symptoms for the first time.

Participants will be randomly divided into two groups:

·         Group A will receive standard pharmacological treatment including a combination of ibuprofen (400 mg), paracetamol (325 mg), and chlorzoxazone (250 mg). They will be monitored regularly for changes in symptoms.

·         Group B will receive photobiomodulation therapy, which uses a specific type of laser light (1064 nm Nd:YAG) applied at a low intensity (0.6 W/cm²) to muscle trigger points for 60 seconds on alternate days. This method is designed to reduce pain and inflammation at the muscle level.

Both groups will be followed up over the course of one month to observe improvements in symptoms. The main goal of the study is to determine which treatment helps relieve pain more effectively and more quickly.

Study Design

Study Type
Interventional
Allocation
Coin toss, Lottery, toss of dice, shuffling cards etc
Masking
Outcome Assessor Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Patients diagnosed as myogenous Temporomandibular joint disorders based on research diagnostic criteria.

Exclusion Criteria

  • 1.Previously treated/ ongoing treatment/ any recurrence.
  • 2.History of Macro trauma 3.Patients with Renal impairment and Hepatotoxicity.

Outcomes

Primary Outcomes

Evaluation of pain reduction

Time Frame: Evaluation of pain reduction- baseline, day 0, 2, 4, 6 (postperatively)

Secondary Outcomes

  • Increase in Mouth Opening(baseline, day-2, day-4, day-6, 1-month, 2-month & 3-month)

Investigators

Sponsor
Dr Javvadi Durga Keerthi Mounavica
Sponsor Class
Other [self]
Responsible Party
Principal Investigator
Principal Investigator

Dr Javvadi Durga Keerthi Mounavica

Vishnu Dental College

Study Sites (1)

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