Diluting With Cerebrospinal Fluid Versus Traditional Intrathecal Administration: Antishivering Effects

Not Applicable

Withdrawn

• Conditions: Antishivering Effects
• Interventions: Procedure: bupivacaine 0.5% 2.5 mL diluting with cerebrospinal fluid

• Registration Number: NCT02189655
• Lead Sponsor: China Medical University, China

Brief Summary

This prospective randomized double-blinded study was conducted to compare the antishivering effects of two different types of intrathecal administration.

Detailed Description

This prospective randomized double-blinded study was conducted to compare the antishivering effects of two different types of intrathecal administration.Group Control:traditional intrathecal administration; Group Diluting:Diluting with cerebrospinal fluid

Study Timeline

• Study First Submitted: 2014-06-30
• Study First Submitted QC: 2014-07-10
• Study First Posted: 2014-07-14
• Study Start: 2016-03
• Status Verified: 2019-11
• Last Update Submitted: 2019-11-18
• Last Update Posted: 2019-11-20
• Primary Completion: 2021-12
• Study Completion: 2021-12

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• American Society of Anesthesiologists (ASA) physical status Ⅰ or Ⅱ who were scheduled for elective surgery under spinal anesthesia were enrolled.

Exclusion Criteria

• Patients with pre-operative fever (>38℃), diabetes, , Parkinson's disease, hypo or hyperthyroidism, Raynaud's syndrome, obese patients (weight >100 kg), patients shorter than 152 cm, those with a history of allergy to the study medications, and patients receiving vasodilators were excluded from the study.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group Diluting with cerebrospinal fluid	bupivacaine 0.5% 2.5 mL diluting with cerebrospinal fluid	Hyperbaric bupivacaine 0.5% 2.5 mL diluting with cerebrospinal fluid was administered intrathecally in 30 seconds

Primary Outcome Measures

Name	Time	Method
antishivering effects of two different types of spinal anesthesia	time point 1: 15 minuntes after spinal anesthesia and time point 2 : when patiets were sent to postoperation care unit	antishivering effects of two different types administration of spinal anesthesia

Trial Locations

Locations (1)

the First Hospital of China Medical University; 🇨🇳 Shenyang, Liaoning, China