Home versus Office blood pressure MEasurements: Reduction of Unnecessary treatment Study

Not Applicable

Completed

• Conditions: Hypertension; Circulatory System

• Registration Number: ISRCTN56551999
• Lead Sponsor: The Netherlands Organisation for Health Research and Development (ZonMw) (The Netherlands)

Brief Summary

2003 Other publications in http://www.ncbi.nlm.nih.gov/pubmed/14763665 2005 Other publications in http://www.ncbi.nlm.nih.gov/pubmed/16257877 2006 Other publications in http://www.ncbi.nlm.nih.gov/pubmed/16877956 2007 Results article in http://www.ncbi.nlm.nih.gov/pubmed/18047914 2007 Results article in http://www.ncbi.nlm.nih.gov/pubmed/17938383

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2004-10-01
• Study Start: 2006-12-06
• Last Update Posted: 7 November 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 430

Inclusion Criteria

1. Males and females aged 18 years and above
2. Average blood pressure between 139 and 200 mmHg for systolic or between 90 and 120 mmHg for diastolic blood pressure
3. Participating subjects are physically and mentally able to measure their own blood pressure
4. Subjects are willing to remain in follow-up during a period of one year
5. Signed informed consent

Exclusion Criteria

1. The presence of clinically manifest cardiovascular events (angina pectoris, heart failure, hypertensive encephalopathy, or prior myocardial infarction or cerebrovascular accident)
2. Severe non-cardiovascular disease (e.g. malignancy), which will interfere with adequate follow up
3. Allergy or contra-indications for the antihypertensive drugs used in this study
4. Serum creatinine above 150 micromol/l
5. Clinically significant orthostatic hypotension (a drop in systolic blood pressure of more than 20 mmHg upon standing)
6. Blood pressure devices

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Blood pressure value (conventional office blood pressure and 24 hour ambulatory blood pressure)<br> 2. Target organ damage (kidney, heart)<br> 3. Cost and number of antihypertensive drugs<br>

Secondary Outcome Measures

Name	Time	Method
<br> 1. Compliance with treatment<br> 2. Quality of life<br>