Screening gestational diabetes: glucose curve versus oral glucose tolerance test
- Conditions
- High suger levels in pregnancy1001842410010273
- Registration Number
- NL-OMON51070
- Lead Sponsor
- Albert Schweitzer Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 158
Pregnant woman and one of the following risk factors, whereas screening for GDM
is necessary:
o GDM in history;
o Body Mass Index (BMI) above 30 kg/m2 before pregnancy;
o An earlier child with a birth weight above 4500 gram or the 95th percentage;
o A first-degree family member with diabetes or GDM;
o Ethnic background: African, Turkish, Hindu, Asian, Latin-American;
o Inta-uterine death in history without a medical explanation;
o Polycystic ovarian syndrome.
All pregnant patients are screened for diabetes with random glucose at the
beginning of the pregnancy before 16 weeks. Patients will be excluded if:
- Diagnosed with diabetes mellitus type 1 or type 2;
- Earlier diagnosed GDM during this pregnancy;
- Age under 18 years;
- Received bariatric surgery in their medical history, as this is a
contra-indication for the OGTT.
Patients will be excluded if they are unable to give written consent or when
there is no proper understanding of Dutch or English.
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary objective is to compare the glucose curve with the OGTT, as a<br /><br>screening test for GDM, which gives the following questions:<br /><br>- Is there any difference in pre-prandial and postprandial capillary blood<br /><br>glucose values between the glucose curve and OGTT, and how are these glucose<br /><br>values related with the diagnosis of GDM? (paragraph 6.3.2)<br /><br>- What are the sensitivity and specificity of glucose curve in relation to the<br /><br>OGTT? </p><br>
- Secondary Outcome Measures
Name Time Method