CIILOS - Continuous Renal Replacement Therapy, Impact on Intensive Care Unit Length of Stay
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 500,000
研究概览
简要总结
This large national cohort study, including over 500,000 patients, where around 5% are treated with continuous renal replacement therapy (CRRT) , aims to evaluate the association between time to initiation of CRRT and intensive care unit (ICU) length of stay (LOS).
详细描述
This large national cohort study, including over 500,000 patients, aims to evaluate the association between time to initiation of continuous renal replacement therapy (CRRT) and intensive care unit (ICU) length of stay (LOS).
The investigators hypothesize that earlier start of CRRT is associated with shorter length of stay among critically ill patients.
CRRT is seen as a costly intervention, and after studies failing to demonstrate a mortality benefit from earlier initiation, the trend is to push, or postpone the start of CRRT. In Sweden the additional cost of CRRT amounts to around 5000 SEK, approximately 500 dollars/euros per 24 hours. However, the 24-hour cost of staying in the ICU is around 58000 SEK or 5800 dollars/euros.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with critical illness
- •Admitted to Swedish ICUs from 2010-2023
- •Adult (18 years or older)
排除标准
- •*Patients under 18 years of age
研究者
Max Bell
MD, PhD, senior lecturer, associate professor
Karolinska Institutet