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Clinical Trials/NCT03365024
NCT03365024
Completed
Not Applicable

Computerized Cognitive Behavioral Treatment for Insomnia: Improving Rural Veteran Access to Evidence-Based Treatment to Reduce Suicide Risk

University of Colorado, Denver1 site in 1 country93 target enrollmentApril 28, 2018

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Insomnia
Sponsor
University of Colorado, Denver
Enrollment
93
Locations
1
Primary Endpoint
Change in Physical Health; Time 1 to Time 3
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

Insomnia is a major problem among veteran populations. Insomnia impacts physical and mental health functioning and is associated with reduced quality of life. Cognitive Behavioral Therapy for Insomnia (CBT-I) is one of the most promising treatments for insomnia; however, access to CBT-I is severely limited by a lack of trained clinicians within the Veterans Health Administration (VHA). There is a critical need to offer innovative approaches to meet the demand and need for insomnia treatment. Leveraging technology to meet treatment demands is consistent with service delivery models based upon stepped care principles. This randomized controlled trial will determine whether a computerized, self-guided, web-based version of CBT-I is efficacious in reducing insomnia symptoms and improving functioning compared to a computerized program control.

Registry
clinicaltrials.gov
Start Date
April 28, 2018
End Date
July 16, 2019
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age between 18 and 89
  • Eligible to receive care through VA ECHCS
  • Reliable access to the Internet
  • English speaking
  • Able to provide informed consent
  • Current insomnia diagnosis as defined by Diagnostic and Statistical Manual of Mental Disorders 5 (DSM 5) criteria

Exclusion Criteria

  • Currently enrolled in/participating in other intervention research studies
  • Other untreated sleep disorders (e.g., sleep apnea, periodic limb movement)
  • Currently receiving formal psychological treatment for insomnia (not including sleep medications)
  • Past 3 month change in schedule and/or dosage of medications that are designed to improve/impact sleep
  • History of Bipolar Disorder (with manic episodes), Schizophrenia, Schizoaffective Disorder, or a Psychotic Disorder
  • Untreated seizures or seizure disorder
  • Physical illness that is active, unstable, degenerative, and/or progressive
  • Currently pregnant or plan to become pregnant in the next 6 months
  • Irregular work schedule, shift work, and/or life changes (e.g., new baby) interfering with regular sleep patterns
  • Significant cognitive impairment, as determined by chart review and/or during screening, that would interfere with ability to engage in SHUTi

Outcomes

Primary Outcomes

Change in Physical Health; Time 1 to Time 3

Time Frame: Baseline and 6 Months

A similar analysis will be performed for the above noted Physical Health summary score, as measured by the Veteran's SF-36, on the change from Time 1 to Time 3 to determine persistence of group differences to six-months post-intervention.

Change in Insomnia Symptom Severity; Time 1 to Time 3

Time Frame: Baseline and 6 Months

A similar analysis will be performed for the above noted insomnia symptom severity outcome on the change from Time 1 to Time 3 to determine persistence of group differences to six-months post-intervention.

Change in Mental Health; Time 1 to Time 2

Time Frame: Baseline and 9 weeks

The primary analysis will be the intent-to-treat comparison between groups of the change in Mental Health summary score, as measured by the Veteran's SF-36, from Time 1 to Time 2. Statistical inference regarding the difference between intervention groups will be based on the estimated coefficient for a group indicator variable in each of three analysis of covariance models with the change from Time 1 to Time 2 for each outcome serving as the dependent variable. Additional covariates will include the baseline value of the outcome to improve the precision of the estimate, and any potential confounders discovered in the randomization check.

Change in Mental Health; Time 1 to Time 3

Time Frame: Baseline and 6 Months

A similar analysis will be performed for the above noted Mental Health summary score, as measured by the Veteran's SF-36, on the change from Time 1 to Time 3 to determine persistence of group differences to six-months post-intervention.

Change in Insomnia Symptom Severity; Time 1 to Time 2

Time Frame: Baseline and 9 weeks

The primary analysis will be the intent-to-treat comparison between groups of the change in insomnia symptom severity as measured by the Insomnia Severity Index (ISI) from Time 1 to Time 2. Statistical inference regarding the difference between intervention groups will be based on the estimated coefficient for a group indicator variable in each of three analysis of covariance models with the change from Time 1 to Time 2 for each outcome serving as the dependent variable. Additional covariates will include the baseline value of the outcome to improve the precision of the estimate, and any potential confounders discovered in the randomization check.

Change in Physical Health ; Time 1 to Time 2

Time Frame: Baseline and 9 weeks

The primary analysis will be the intent-to-treat comparison between groups of the change in Physical Health summary score, as measured by the Veteran's SF-36, from Time 1 to Time 2. Statistical inference regarding the difference between intervention groups will be based on the estimated coefficient for a group indicator variable in each of three analysis of covariance models with the change from Time 1 to Time 2 for each outcome serving as the dependent variable. Additional covariates will include the baseline value of the outcome to improve the precision of the estimate, and any potential confounders discovered in the randomization check.

Study Sites (1)

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