Evaluating the systemic level of inflammation in Relation to the perioperativ Outcome of Patients with pre-existing cardiovascular diseases in non-cardiac surgery
Recruiting
- Conditions
- Aneurysms of the descending thoracic aorta and/or abdominal aorta
- Registration Number
- DRKS00029162
- Lead Sponsor
- Charité Campus Benjamin FranklinKlinik f. Anästhesiologie m. S. operative Intensivmedizin
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
planned, open vascular surgery of the aorta
Revised Cardiac Index >=2
Exclusion Criteria
Pregnancy, lactation, participation in any other prospective interventional study during participation in this study.
Patients who are incapable of giving consent.
Patients who are in hospital because of an administrative order.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method This pilot study - in the context of clinical routine - is intended to estimate the effect and the case number planning for subsequent studies.<br>The following endpoints will be registered: Vital signs and their indices (oxygen saturation, blood pressure, heart rate, heart rhythm, cardiac index, stroke volume, stroke volume variation, stroke volume index, pulse pressure variation, central venous pressure, lactate, base excess, haemoglobin content, creatinine concentration, central venous saturation, diuresis), duration of surgery, anaesthesia duration, ventilation duration, ventilation parameters, intraoperative blood loss, need for blood products, catecholamine doses, incidence of organ complications, duration of dialysis, echocardiography parameters (presence of pericardial effusion, size of atria and ventricles, presence of vitia, ejection fraction, assessment of heart valves), cytokine levels, length of stay (ICU, hospital).
- Secondary Outcome Measures
Name Time Method