Efficacy of coronary artery calcification on Denosumab

Phase 4

• Conditions: Patients with osteoporosis with coronary artery calcification; osteoporosis, coronary artery calcification

• Registration Number: JPRN-jRCT1031190025
• Lead Sponsor: Kubota Naoki

Brief Summary

This study was suspended due to difficulty in securing the required number of patients.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-05-20
• Study Completion: 2020-12-18
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 1

Inclusion Criteria

Patients (>20 years old) with osteoporosis with coronary artery calcification

Exclusion Criteria

Patients who can not enforce coronary artery CT, patients with baseline coronary calcification score of 0 or 1000 or more, secondary osteoporosis patients, patients with severe renal impairment(eGFR<35mL/min).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percent change in coronary artery calcification score at 48 weeks after intervention

Secondary Outcome Measures

Name	Time	Method
Degree of improvement of bone density by DXA at 48 weeks after intervention<br>Percent change in coronary volume score at 48 weeks after intervention