Targeted therapy to improve outcomes following stroke

Not Applicable

Withdrawn

• Conditions: Stroke; Neurological - Other neurological disorders

• Registration Number: ACTRN12607000597493
• Lead Sponsor: niversity of Auckland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-11-20
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Withdrawn
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

First ever monohemispheric stroke between 6 and 12 weeks prior to inception
Upper limb weakness
National Institutes of Health Stroke Scale score between 2 and 16 at inception
Medically stable
Ambulatory

Exclusion Criteria

Contraindications to Transcranial Magnetic Stimulation or Magnetic Resonance Imaging
Medications known to alter neural excitability
Cognitive impairment precluding informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
pper limb function as assessed by a blinded clinical assessor with the Action Research Arm Test[Immediately prior to, and following, administration]

Secondary Outcome Measures

Name	Time	Method
Grip and load forces during a precision grip-lift task.[Immediately prior to, and following, administration];Primary motor cortex excitability, assessed with transcranial magnetic stimulation[Immediately prior to, and following, administration]