Safety and tolerability of sodium thiosulfate in patients presenting with an acute coronary syndrome undergoing coronary angiography via radial approach: a dose-escalation study. - safe acs

niversitair Medisch Centrum Groningen0 个研究点目标入组 18 人开始时间: 待定最近更新: 2024年2月28日

试验速览

Trial is onging in other countries

•- Age * 18 years;
•-The diagnosis ACS defined by: chest pain suggestive for myocardial ischemia for at least 30 minutes, the time from onset of the symptoms less than 24 hours before hospital admission, with (STEMI) or without (nSTEMI/iAP) an electrocardiogram (ECG) recording with ST- segment elevation of more than 0.1 mV in 2 or more contiguous leads;
•-cardiac catheterization via radial approach is being considered;
•- Patient is willing to cooperate with the trial during hospitalization.

•- Known cardiomyopathy or LVEF < 35%;
•- History of a malignancy treated with chemo- and/or radiotherapy < 1 year;
•- Systolic blood pressure under 100mmHg or over 180mmHg at presentation;
•- Cardiogenic shock at presentation? (def: SHOCK II)
•- Sedated and/or intubated patients;
•- The existence of a condition with a life expectancy of less than 1 year;
•- pregnant or breastfeeding at time of presentation;
•- A condition which, according to the clinical judgment of the investigator and/or treating physician, does not allow the patient to successfully participate in the study.

发起方