Role of Nerve Mobilizations in Decreasing Pain and Disability Among Patients With Cervical Radiculopathy

Not Applicable

Completed

• Conditions: Cervical Radiculopathy
• Interventions: Other: Conventional physical therapy; Other: Nerve mobilization

• Registration Number: NCT04896749
• Lead Sponsor: University of Lahore

Brief Summary

Objective of the study is to find out the effectiveness of nerve mobilization in patients with cervical radiculopathy. It is a single blinded randomized controlled trial using non-probability convenient sampling. Data is collected from University Physical therapy and Rehabilitation Clinic, University of Lahore, Pakistan.

Alternate hypothesis: There is a significant role of nerve mobilizations in decreasing pain and disability among patients with cervical radiculopathy.

Null hypothesis: There is no significant role of nerve mobilizations in decreasing pain and disability among patients with cervical radiculopathy.

.

Detailed Description

It will be a prospectively registered, parallel designed, randomized controlled trial with concealed allocation, conducted in University Physical Therapy and Rehabilitation Clinic, Lahore, Pakistan. Patients who met the eligibility criteria will be informed about the aim of the study. All eligible participants who will agree to participate in the study signed the consent form. Eligibility of the participants will be determined by the two members of the research team before the randomization. After baseline assessment, eligible patients will be randomly assigned (in a 1:1 ratio) into two groups (Group A and Group B). Randomization will be done by one of the research team members using fish bowl method. Randomization assignments will be kept in opaque, sealed envelopes and unsealed by the researchers after baseline testing. Outcome assessor will be masked to group allocation and patients will be instructed not to talk about the content of their exercise program during the post intervention visit and could contact their therapists in case of any problems during trial participation. Help of female physiotherapist will be taken for the female patients. The sample size was calculated as 76 participants (38 per group), allowing statistical power of 80%, an alpha level of 5% and attrition rate of 20% having mean difference of 1.1 and SD of 1.48 and 1.63.

Study Timeline

• Study First Submitted: 2021-04-08
• Study First Submitted QC: 2021-05-17
• Study First Posted: 2021-05-21
• Study Start: 2021-06-01
• Primary Completion: 2021-08-13
• Study Completion: 2021-08-16
• Status Verified: 2021-11
• Last Update Submitted: 2021-11-17
• Last Update Posted: 2021-11-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

• Male and female patients with age between 20 to 45 years
• Patients having pain for more than 4 months
• Patients having positive upper limb neurodynamic test
• Patient with positive spurling test.

Exclusion Criteria

• Patients with trauma of upper limb and cervical spine
• Dizziness
• Upper limb circulatory disturbance
• Malignancy
• Patients with bilateral symptoms

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group B/ Conventional physical therapy group	Conventional physical therapy	In this group, patients will receive routine physical therapy and also given home plan for cervical isometric exercises
Group A/ Nerve mobilization group	Nerve mobilization	In this group, patients will receive nerve mobilization exercises along with routine physical therapy. Patients will also be given home plan for cervical isometric exercises.

Primary Outcome Measures

Name	Time	Method
Upper extremity functional index (assessing change in ability to do activities with upper limb at baseline and at 4th week of treatment)	Baseline and at 4th week	It is a patient reported outcome measure used to assess the functional impairment in individuals with upper limb dysfunction. Total score is 80. Greater the score, better the condition of patients.
Numeric pain rating scale (to assess change in pain at between baseline and at 4th week of treatment)	Baseline and at 4th week	Used for scoring pain level of individual. it is scored 0 to ten.Zero being the lowest pain level, 10 being worst pain level.The patient is asked to make three pain ratings, corresponding to the pain experienced over the past 24 hours.; The average of the 3 ratings was used to represent the patient's level of pain over the previous 24 hours.
Neck Disability Index scale (to assess the change in disability due to neck pain at baseline and at 4th week of treatment)	Baseline and at 4th week	This scale is used for accessing how the neck pain is affecting the ability to manage everyday life activities.The NDI can be scored as a raw score or doubled and expressed as a percent. Each section is scored on a 0 to 5 rating scale, in which zero means 'No pain' and 5 means 'Worst imaginable pain'. Points of total 10 questions are summed to a total score.Greater score indicates greater disability.

Trial Locations

Locations (1)

University Physical Therapy and Rehabilitation Clinic; 🇵🇰 Lahore, Punjab, Pakistan