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临床试验/NCT00659087
NCT00659087已完成4 期

A Pilot Study of the Feasibility of Early Discharge After Total Knee Arthroplasty Using a Femoral Nerve Block

Edmonton Civic Employees Research Fund1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2008年4月1日最近更新:
适应症
干预措施

试验速览

阶段
4 期
状态
已完成
发起方
入组人数
20
试验地点
1
主要终点
knee flexion

研究概览

简要总结

Hospital stays after total joint replacement surgery have been getting shorter over the past 10 years. This is mostly due to new ways to manage pain and early rehabilitation. To be able to go home safely soon after surgery, patients need to:

    1. have adequate pain control
    1. be able to move through activities of daily living on their own (using aids)

Femoral nerve block, in combination with pain medications, is one of the new treatment strategies that are currently being used at other hospitals in Canada, the United States and the United Kingdom. Nerve blocks involve a needle filled with local anesthetic into the nerve that allows the feeling of pain around the knee. With good pain management, patients will be able to more quickly bend their knee and regain the ability to walk with aids and move from sitting and lying positions to standing and walking. Once they can do these activities with adequate pain control, they can be discharged from hospital to continue recovery at home. The purpose of this study is to examine a new way of managing postoperative pain and encourage early knee flexion and mobility, while maintaining pain control for patients after total knee replacement. We believe that patients who receive the nerve block in addition to the regular pain medication will have more knee flexion at discharge and experience less pain than patients who only receive usual pain medications.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Single Group
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

性别
All
接受健康志愿者
否

入选标准

  • •Undergoing primary total knee arthroplasty
  • •English-speaking
  • •Preoperative knee ROM > 90 degrees
  • •Body Mass Index < 40

排除标准

  • •Regular preoperative opioid use
  • •Hepatic insufficiency
  • •Any contra-indications to receiving a femoral block

研究组 & 干预措施

Femoral Block

Experimental

Those receiving femoral block in addition to usual pain management

干预措施: Femoral Block (Procedure)

Usual Care

Active Comparator

Those receiving only usual pain management without a femoral block

干预措施: Usual Care (Other)

结局指标

主要结局

knee flexion

时间窗: at hospital discharge or day 4 postoperatively, whichever is earlier

次要结局

  • nausea/vomiting(during hospitalization)
  • participation in rehabilitation(day of surgery)
  • pain(daily in hospital, 2 weeks, 6 weeks, 12 weeks)
  • length of hospital stay(during hospitalization)

研究者

发起方
Edmonton Civic Employees Research Fund
申办方类型
Other
责任方
Principal Investigator
主要研究者

Tsui, Ban / Johnston DWC

Pediatric and Adult Anesthesiologist, Associate Professor/Director of Clinical Research, Stollery Children's Hospital/University of Alberta Hospital

Edmonton Civic Employees Research Fund

研究点 (1)

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