Comparison of the effect of intravenous and intra-cuff magnesium on post-extubation tracheal morbidity.

Dr Naa Martekuor Vanderpuye0 sites96 target enrollmentStarted: November 18, 2022Last updated: May 29, 2023

Conditions

Trial Snapshot

No summary available.

•1.Patients above 18 years requiring endotracheal intubation
•2.Patients with BMI <30
•3.Patients with ASA classification I or II
•All elective general surgery patients requiring endotracheal intubation who meet above inclusion criteria and give a signed or thumb-printed informed consent to participate in this study will be included except:

•Patients < 18years because they are incapable of giving informed consent by law.
•Patients > 18years of age who are mentally incapacitated.
•Patients with ASA III and IV, as these may be too sick with uncontrolled co-morbidities.
•Patients who have an Upper Respiratory Tract Infection prior to surgery (sore throat, cough, running nose), as these may make assessment of tracheal morbidities difficult.
•Patients coming for head and neck surgeries as manipulations during these surgeries could in themselves cause laryngeal morbidity.
•Patients who will have their surgical cases done in the prone position.
•Patients with a history of Asthma. These patients have a reactive airway and are prone to airway complications during intubation.
•Patients with a history of difficult intubations, anticipated difficult intubation, and those who will have multiple attempts at intubation.
•Patients with known anatomical laryngo-tracheal abnormalities, snoring and gastroesophageal reflux.
•Patients who will require post-operative intubation and so cannot have the occurrence of tracheal morbidity 24 hours post-operatively assessed.
•Patients who are obese (BMI >35kg/m2) ( they are high risk for difficult intubation and ventilation as well as develop airway complications more easily)

Sponsor

Dr Naa Martekuor Vanderpuye