Stress and childhood epilepsy - Stress and childhood epilepsy

niversitair Medisch Centrum Utrecht0 个研究点目标入组 123 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

暂无简介。

•Children with epilepsy:
•- Patients between 6 to 17 years of age
•- Established diagnosis of epilepsy
•- Mean seizure frequency of at least 1 seizure a year
•Healthy controls:
•- Age and gender matched to a child with epilepsy that is included in the study, not diagnosed with any chronic disease

•o In patients with epilepsy:
•-Any doubt about the diagnosis epilepsy
•-No distinction possible between (co-existing) seizures of (possible) non-epileptic origin and epileptic seizures by parents and/or treating paediatric neurologist
•- Seizure free since brain surgery or brain surgery scheduled in the following months
•- Reported status epilepticus in response to acute stress;in total study population:
•- Children with assessed or expected (based on school level) intelligence quotient (IQ) or IQ estimate (calculated from developmental age) <70
•- Children with chronic co morbidities (e.g. psychiatric disorder)
•- Use of medication known to influence HPA-axis functioning (e.g. oral anticonceptives, corticosteroid medication, ACTH receptor agonists)
•-Heavy smoking (> 10 cigarettes a day)
•-Heavy alcohol consumption (> 60g a day)

发起方

niversitair Medisch Centrum Utrecht