Evaluation of the Effect of Preoperative Symbiotic Bowel Conditioning on Surgical Site Infection After Elective Colorectal Surgery
Early Phase 1
- Conditions
- Postoperative Wound Infection
- Interventions
- Biological: Symbiotic
- Registration Number
- NCT01413659
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
The objective of the study is to investigate whether peri-operative symbiotic treatment could reduce the risk of postoperative infections in patients undergoing elective colorectal surgery. This study was also designed to assess the risk-adjusted incidence and predictors of surgical site infections.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 150
Inclusion Criteria
- Both genders
- More than 14 years old
- Candidate for elective colorectal surgery
Exclusion Criteria
- Denied written informed consent,
- Severe neutropenia, and
- Critically ill condition
- Not meeting inclusion criteria
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Symbiotic Symbiotic Symbiotic is a combination of prebiotics and probiotics that is designed to have synergistic or additive effects benefiting the host
- Primary Outcome Measures
Name Time Method Frequency of post-operative infection after elective colorectal surgery among patients with and without pre-operative symbiotic conditioning. 15 months
- Secondary Outcome Measures
Name Time Method The incidence of postoperative infection including surgical site infections (SSIs) and distant-site infections after elective colorectal surgery in patients whether or not receiving pre-operative symbiotic conditioning. 15 months