Yi Jin Jing Tiger Roaring Speech Rehabilitation With Real-Time Feedback Technique for Treatment of Speech Disorders in Parkinson's Disease: A Perspective Cohort Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Speech Disorders
- Sponsor
- Ruijin Hospital
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Differences in Voice Handicap Index (VHI) between treatment conditions in the on- and off- medication states
- Last Updated
- 5 years ago
Overview
Brief Summary
Speech disorders affect more than 90% of patients with Parkinson's disease (PD). Neither of conventional drugs nor surgery can effectively improve speech function. Western speech rehabilitation is effective for speech disorders, but the domestic use of those methods used is limited. Our preliminary results revealed that traditional Chinese Yi jin jing tiger roaring speech rehabilitation is effectively in the treatment of speech disorders in PD, however, high-quality clinical evidence is still scarce. In order to solve this problem, we will conduct a prospective cohort study to explore the effects of Yi Jin Jing tiger roaring speech rehabilitation with real-time feedback technique on speech disorders in PD patients. This study will help to establish a set of Chinese Medicine treatment and objective evaluation methods for PD speech disorders.
Investigators
Bomin Sun
Chief physician
Ruijin Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients with idiopathic Parkinson's disease
- •Native language is Chinese
- •VHI-10 score more than 10
- •informed consent
Exclusion Criteria
- •Previous or concurrent medical history affecting swallowing function (laryngeal diseases such as vocal nodules, gastroesophageal reflux, and laryngeal cancer).
- •History of serious psychosis
- •Diagnosed by the investigators that patients with severe cardiac, liver and kidney diseases, or other serious health conditions
- •Dementia (A Mini-Mental State Examination (MMSE) score of \< 24), inability to comprehend the experimental protocol or voluntarily provide informed consent
- •Lack of cooperation
- •Additional reasons for exclusion at the discretion of the clinical investigator
Outcomes
Primary Outcomes
Differences in Voice Handicap Index (VHI) between treatment conditions in the on- and off- medication states
Time Frame: Baseline, 1 week, 2 weeks, 3 weeks, 4 weeks
The Voice Handicap Index is a self-administered instrument, comprising 30 items on voice-related dysfunction. VHI has a range of 0 (normal voice function) to 120 (severe voice dysfunction).
Secondary Outcomes
- Differences in voice parameters between treatment conditions in the on- and off- medication states(Baseline, 1 week, 2 weeks, 3 weeks, 4 weeks)
- Differences in Burg Balance Scale (BBS) scores between two treatment conditions in the on- and off- medication states.(Baseline, 1 week, 2 weeks, 3 weeks, 4 weeks)
- Differences in Beck Depression Inventory (BDI) scores between Treatment conditions.(Baseline, 4 weeks)
- Differences in Beck Anxiety Inventory (BAI) scores between treatment conditions.(Baseline, 4 weeks)
- Differences in Swallowing Disturbance Questionnaire (SDQ) scores between treatment conditions in the on- and off- medication states.(Baseline, 1 week, 2 weeks, 3 weeks, 4 weeks)
- Differences in Water Swallow Test (WST) scores between treatment conditions in the on- and off- medication states.(Baseline, 1 week, 2 weeks, 3 weeks, 4 weeks)
- Differences in 8-item Parkinson's Disease Questionnaire (PDQ-8) scores between treatment conditions.(Baseline, 4 weeks)