Saline Nasal Irrigation For acute Sinusitis (SNIFSII)

niversity of Southampton0 sites108 target enrollmentJune 11, 2019

Overview

No summary available.

Registry

who.int

Start Date

June 11, 2019

End Date

June 30, 2021

Last Updated

4 years ago

Study Type

Interventional

Sex

All

Sponsor

niversity of Southampton

•The researchers pragmatically define acute sinusitis as having sinus discomfort and at least 2 other symptoms (2 of: patient\-reported nasal obstruction, patient\-reported purulent nasal discharge, or pus seen in the nasal cavity on inspection by the clinician).
•They do not propose using prior duration (e.g. the requirement for at least 7 days without improvement in the Canadian guidelines) since there is no good evidence for a particular cut\-off, and their aim is to help people who are currently being treatment with antibiotics for sinusitis, many of whom present with 7 days.

•1\. Inability to complete outcomes (reduced capacity: dementia, severe uncontrolled mental illness; terminal illness etc)
•2\. Head/neck cancer
•4\. Immune\-suppressive treatment
•5\. Cystic fibrosis
•6\. Pregnancy/breastfeeding
•7\. Other nasal disorders e.g. polyps; poor gag/swallow reflexes