Study of Frailty Among Renal Transplant Recipients, Its Relation to Chronic Renal Allograft Dysfunction
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Assessment of frailty
研究概览
简要总结
The aim of the study is to assess prevalence of frailty among renal transplant recipients in Alexandria University Hospitals and to study the relation between frailty and chronic allograft dysfunction.
详细描述
With respect to correlates of frailty, although higher comorbidity burden is also a risk factor for frailty among KT candidates, frailty can also occur in the setting of lower comorbidity burdens. Diabetes and serum albumin concentration are also associated with frailty among prevalent dialysis patients.
In addition, individuals with CKD and ESKD who are frail are also more likely to have cognitive impairment and sarcopenia, or low muscle mass, than their non-frail counterparts
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Renal transplanted patients with GFR more than 30
排除标准
- •Mentally or physically unfit patients.
- •Amputation of lower limb.
- •Active neoplasia, chronic liver disease, previous immunological disease.
- •Psychiatric disorders.
- •Pregnancy.
研究组 & 干预措施
renal transplant patients
patients will be subjected to:
- Assessment of frailty by Clinical Frailty Scale.
- Assessment of nutritional status using Patient Generated Subjective Global Assessment (PG-SGA).
- Comorbidity assessment using Charlson comorbidity score.
- Six minutes walk test.
- Muscle strength assessment using hand grip strength (HGS) dynamometer.
干预措施: assessment of frailty (Diagnostic Test)
结局指标
主要结局
Assessment of frailty
时间窗: 30 days
by Clinical Frailty Scale.
次要结局
- Assessment of nutritional status(30 days)
- Comorbidity assessment(30 days)
- Muscle strength assessment(30 days)
研究者
Mohamed Mamdouh Mahmoud Mohamed Elsayed , MD
Associate professor
Alexandria University