Effects of procalcitonin-guided antimicrobial stewardship on reduction of antibiotical use in patients with severe sepsis or septic shock: a retrospective analysis.

• Conditions: A41.9; R57.2; Sepsis, unspecified; Septic shock

• Registration Number: DRKS00003490
• Lead Sponsor: Klinik für Anästhesiologie , operative Intensivmedizin und SchmerztherapieKrankenhaus Düren

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2011-12-15
• Study Start: 2012-02-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 141

Inclusion Criteria

Severe sepsis and septic shock under antibiotic therapy

Exclusion Criteria

known pregnancy; bone-marrow transplant or patient under chemotherapy; infections for which long-term antibiotic treatment is strongly recommended (e.g. infective endocarditis, tuberculosis, anterior mediastinitis after cardiac surgery) and do- not-resuscitate orders

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Retrospective analyses<br>1. 28-day-Mortality<br>2. Days on Antibiotictherapy

Secondary Outcome Measures

Name	Time	Method
1. Lenght of stay in Intensiv Care Unit 2. Ventilation hours 3. Re-infection rate 4. antibiotic cost