Analysis of the difference of adverse reactions between oral immunotherapy protocols in patients with food allergy
- Conditions
- Injury, poisoning and certain other consequences of external causes
- Registration Number
- KCT0007260
- Lead Sponsor
- Samsung Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 100
? If one or more of eggs, milk, and wheat were positive in the food oral provocation test conducted within 12 months from the time of obtaining consent
? If food specific IgE (Uni-CAP) is 0.35 or higher within 12 months from the time of consent
? Subject and/or guardian consent to participate in the study
* Patients who cannot stop taking drugs (systemic steroids, immunosuppressants, immunotherapeutics, biologics, etc.) that may affect the food oral provocation test and skin prick test for a period that may affect the test
* Patients who need to continue taking drugs that may aggravate symptoms during anaphylaxis (beta-blockers, angiotensin-converting enzyme (ACE) inhibitors, angiotensin-receptor blockers (ARB) or calcium channel blockers)
* Patients with severe cardiopulmonary disease requiring continuous treatment
* Patients with systemic diseases requiring a specific diet
* However, if anaphylaxis occurs after ingestion of eggs, milk, or wheat, it does not fall under the exclusion criteria.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method tolerance;adverse effect of oral immunotherapy
- Secondary Outcome Measures
Name Time Method Specific IgE and specific IgG4;covariant factors influencing tolerance;psychological state following oral immunotherapy