Endothelial Dysfunction in Diabetes Mellitus
Phase 2
- Conditions
- Diabetes Melitus Type 1.Insulin-dependent diabetes mellitus
- Registration Number
- IRCT138811033138N1
- Lead Sponsor
- Vice Chanceller of Research,Isfahan University of Medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
1) Children with diabetes type 1 with at least 1 yr duration. 2) Age >5 yr and < 20 yr. 3) No other systemic diseases. 4) No drug use other than insulin. 5) No hypoglycemia or ketosis during past 48 hr. 6) No smoking. 7) No pregnancy.
Exclusion criteria: Uncooperae patient
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Endothelial dysfunction. Timepoint: 0, 8, 10, 18 weeks. Method of measurement: ICAM, VCAM, vwf.
- Secondary Outcome Measures
Name Time Method ipid profile. Timepoint: 0, 8, 10, 18 weeks. Method of measurement: Trigliceride, cholesterol, HDL-c, LDL-c.;Microalbuminuria. Timepoint: 0, 8, 10, 18 weeks. Method of measurement: Urine microalbumin and creatinine.