Association between Hand function and cognition in patients with Diabetic Polyneuropathy
- Conditions
- Polyneuropathy in diseases classified elsewhere,
- Registration Number
- CTRI/2021/03/032084
- Lead Sponsor
- College of Physiotherapy Dayananda Sagar University
- Brief Summary
1.Type 2 Diabetes Mellitus subjects present with various sensory deficits, balance issues and foot ulcers as well. A lot of studies have been done with regard to improving balance and mobility but very less studies have explored the effect of cognition in the type 2 DPN subjects.
The incidence of neurodegenerative diseases associated with age is increasing.
Cognitive dysfunction in individuals with diabetes can result from interactions between inherent metabolic abnormalities , such as hyperglycemia, hyperinsulinaemia, and micro and macrovascularcomplications in addition to hypertension , dyslipidemia , depression and obesity.
2. Upper limb function is one of the strong indicators of quality of life in the T2DM population as .Dexterity is that trait in humans that determines hand function. Thus it seems necessary to understand the impact of neurodegeneration on hand dexterity & hand function which are very essential while executing everyday functional activities.
Manual dexterity measures can be useful for early detection of age related functional decline.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 64
Diagnosed with Diabetic Polyneuropathy by a Podiatrist Ability to see with glasses.
History of stroke Use of antiepilepric medications , neurotropic agents or psychotropic agents that could interfere in the cognitive tests Glycated haemoglobin (A1c) level below 4.0% Known neurodegenerative diseases like Parkinson’s Disease or Alzheimers Disease, MND , Spinal Muscular Atrophy etc Orthopaedic disorders of upper limb that can affect manual dexterity : Cervical pathology, Shoulder pathology etc Diabetic retinopathy.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Nine Hole Peg Test for Manual Dexterity One time
- Secondary Outcome Measures
Name Time Method Montreal Cognitive Assessment ( MoCA) for Domain Specific Cognition One time
Trial Locations
- Locations (1)
Karnataka Institute of Endocrinology and research
🇮🇳Bangalore, KARNATAKA, India
Karnataka Institute of Endocrinology and research🇮🇳Bangalore, KARNATAKA, IndiaNandhini SPrincipal investigator9972036965nandusgowda18@gmail.com