Use of Near Infrared Spectroscopy to Measure Intracranial ScvO2

Not Applicable

Completed

• Conditions: Healthy
• Interventions: Other: Use of impedance threshold device during spontaneous ventilation

• Registration Number: NCT01746576
• Lead Sponsor: University of Virginia

Brief Summary

The purpose of this study is to determine whether analysis of near infrared absorbance signals that occur at different frequencies might provide information about the difference in oxygen saturation between arterial and venous blood.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-09
• Study First Submitted: 2012-10-29
• Status Verified: 2012-12
• Study First Submitted QC: 2012-12-07
• Study First Posted: 2012-12-11
• Primary Completion: 2013-09
• Study Completion: 2013-09
• Last Update Submitted: 2014-04-15
• Last Update Posted: 2014-04-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Adult 18-65 years of age

Exclusion Criteria

• Dilated cardiomyopathy
• Congestive heart failure
• Pulmonary hypertension
• Severe aortic stenosis
• Flail chest
• Chest pain
• Shortness of breath

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
All	Use of impedance threshold device during spontaneous ventilation	All subjects will undergo spontaneous ventilation through an impedance threshold device and ScvO2 will be recorded before and after

Primary Outcome Measures

Name	Time	Method
Estimated venous oxygen saturation	From 5 to 6:59 minutes after applying the impedance threshold device	Oxygen saturation will be calculated from the five minute period of time prior to use of the impedance threshold device (0-4 mins), and then again in the 2 minute period after the impedance threshold device is applied (5-6 mins)

Trial Locations

Locations (1)

University of Virginia; 🇺🇸 Charlottesville, Virginia, United States