Intra Testicular Artery Injection of Bone Marrow Stem Cell in Management of Azoospermia
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Semen Analysis
研究概览
简要总结
Azoospermia due to low sperm production (non-obstructive azoospermia) affects approximately 1% of the male population and 10% of men who seek fertility evaluation. Testis biopsy reveals that these men have Sertoli cell-only pattern, maturation arrest, or hypospermatogenesis. Until recently, it was assumed that men with non-obstructive azoospermia were untreatable. Indeed, these patients were often referred to as being "sterile" or having "testicular failure." We start to use stem cell in treatment of such patients by injecting the stem cell at the testis and the testicular artery in one group and at the testis only in other group
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •- Azoospermia
排除标准
- •- Absent or surgical removed testes
研究组 & 干预措施
Bone marrow stem cell injection
through special butterfly inject stem cell in testicular artery and inside tubules
干预措施: Bone marrow stem cell injection (Procedure)
结局指标
主要结局
Semen Analysis
时间窗: Three to six months
After stem cell injection by three to six months we evaluate the outcome by semen analysis
次要结局
- Inhibin B Hormone(Three to six months)
研究者
Khaled Abdulmoneim Gadalla
Prof Dr
Man Clinic for Andrology, Male Infertility and Sexual Dysfunction