NCT01688219已完成不适用
Immune Mechanisms During SAPHO Syndrome and Treatment by Etarnecept
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 39
- 主要终点
- IL-8 production by PMN
研究概览
简要总结
The aetiology of SAPHO syndrome seems to involve genetic, infectious and immunological components. The investigators examined innate and adaptative immune responses in SAPHO syndrome as compared with psoriatic arthritis and rheumatoid arthritis.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Year 至 70 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Clinical diagnosis of SAPHO syndrome
- •Must have bone lesions
排除标准
- •Infliximab treatment
结局指标
主要结局
IL-8 production by PMN
时间窗: 24 h
次要结局
- TNFalpha production by PMN(24 h)
研究者
相似试验
已完成
不适用
Study of Psoriatic ArthritisPsoriasisPsoriatic ArthritisNCT00001420National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)999
已完成
不适用
Clinical outcomes of an inflammatory bone disorder that may be associated with skin disorders.Synovitis Acne Pustulosis Hyperostosis and Osteitis syndromeInflammatory and Immune System - Autoimmune diseasesMusculoskeletal - Other muscular and skeletal disordersACTRN12619000445178Graeme Carroll21
进行中（未招募）
不适用
Phenotyping Mitochondrial and Immune Dysfunction in POTS With Targeted Clinical Intervention.Postural Tachycardia SyndromeNCT05409651University of California, San Diego25
已完成
不适用
Immune Abnormalities in Sporadic Inclusion Body MyositisSporadicInclusion BodyMyositisNCT00030212National Institute of Neurological Disorders and Stroke (NINDS)80
招募中
不适用
Novel Genetic Disorders of the Immune SystemPI3KCDCTLA4STAT3GOFMAGT1NCT02257892National Institute of Allergy and Infectious Diseases (NIAID)500