Immune Response in the SAPHO Syndrome

Completed

• Conditions: SAPHO Syndrome

• Registration Number: NCT01688219
• Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Brief Summary

The aetiology of SAPHO syndrome seems to involve genetic, infectious and immunological components. The investigators examined innate and adaptative immune responses in SAPHO syndrome as compared with psoriatic arthritis and rheumatoid arthritis.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-11
• Status Verified: 2007-10
• Study Completion: 2008-05
• Study First Submitted: 2012-09-14
• Study First Submitted QC: 2012-09-18
• Last Update Submitted: 2012-09-18
• Study First Posted: 2012-09-19
• Last Update Posted: 2012-09-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 39

Inclusion Criteria

• Clinical diagnosis of SAPHO syndrome
• Must have bone lesions

Exclusion Criteria

• Infliximab treatment

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
IL-8 production by PMN	24 h

Secondary Outcome Measures

Name	Time	Method
TNFalpha production by PMN	24 h