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Clinical Trials/CTRI/2019/08/020875
CTRI/2019/08/020875
Other
未知

A Pilot project for assessment of safety and efficacy of miltefossine in the treatment of Acanthamoeba Keratitis

V Prasad Eye Institute0 sites0 target enrollmentTBD
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ConditionsHealth Condition 1: H160- Corneal ulcer

Overview

Phase
未知
Intervention
Not specified
Conditions
Health Condition 1: H160- Corneal ulcer
Sponsor
V Prasad Eye Institute
Status
Other
Last Updated
4 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
4 years ago
Study Type
Interventional

Investigators

Sponsor
V Prasad Eye Institute

Eligibility Criteria

Inclusion Criteria

  • •1\.Age equal to or more than 18 years.
  • •2\) Male or female
  • •3\) Stromal infiltrate size between \<6 mm and involving anterior to mid stroma only.
  • •4\) Corneal scraping positive for Acanthamoeba cysts in direct smear examination by any one or more of the methods used.

Exclusion Criteria

  • •1\) The corneal scrapings are negative for Acanthamoeba.
  • •2\)The patient has a history of allergy to Miltefosine
  • •3\) The cornea or sclera has been perforated or perforation is impending.
  • •4\)The unaffected eye is legally blind. .
  • •5\)The patient is known to be HIV positive or diabetic.
  • •6\)The initial culture shows significant growth of bacteria ( \>10 colonies) or fungus.
  • •7\)Both eyes are infected.

Outcomes

Primary Outcomes

Not specified

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