Effect of Radical Prostatectomy on Involuntary Pelvic Floor Muscle Contraction
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Lower Urinary Tract Symptoms
- Sponsor
- Pierre and Marie Curie University
- Enrollment
- 22
- Locations
- 1
- Primary Endpoint
- Latency (time)
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
This study evaluate the effect of radical prostatectomy on involuntary pelvic floor muscle contraction
Detailed Description
Radical prostatectomy may cause stress urinary incontinence (SUI). That poses problem in terms of quality of life. There are many treatment options available for patients with SUI, but the exact mechanism is not known. We compared, in continent and incontinent men post-radical prostatectomy, the correlation between the temporal course of pelvic floor activation during cough. Simultaneously, recordings of electromyographic activity of external anal sphincter (EAS EMG) and external intercostal muscle (EIC EMG) during coughing will be made with a pair of pre-gelled electrodes. Cough effort cause an involuntary pelvic contraction. Intercostals muscles recording was chosen because they are one of the muscular components of cough initiation with diaphragm muscle. 24h pad-weighing test is used to quantify urinary incontinence. We will measure the latency between the onset of the EIC EMG and the EAS EMG (RT3), during a cough effort. We will also measure the duration of the contraction, the maximum EAS EMG activity and the area under the curve.
Investigators
Gérard Amarenco
Head of Neuro-Urology department, Tenon hospital
Pierre and Marie Curie University
Eligibility Criteria
Inclusion Criteria
- •Follow in neuro-urology for lower urinary tract symptoms
- •Radical Prostatectomy
Exclusion Criteria
- •Perineal Radiotherapy
- •Surgery for stress urinary incontinence
Outcomes
Primary Outcomes
Latency (time)
Time Frame: 1 day: During electromyographic recording
The time (latency) between the onset of the external intercostal muscle (EIC EMG) and the electromyographic activity of external anal sphincter (EAS EMG), during a cough effort.
Secondary Outcomes
- Duration (time)(1 day: During electromyographic recording)
- Maximum(1 day: During electromyographic recording)
- Area under the curve(1 day: During electromyographic recording)