Effect of Radical Prostatectomy on Involuntary Pelvic Floor Muscle Contraction
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 22
- 试验地点
- 1
- 主要终点
- Latency (time)
研究概览
简要总结
This study evaluate the effect of radical prostatectomy on involuntary pelvic floor muscle contraction
详细描述
Radical prostatectomy may cause stress urinary incontinence (SUI). That poses problem in terms of quality of life. There are many treatment options available for patients with SUI, but the exact mechanism is not known. We compared, in continent and incontinent men post-radical prostatectomy, the correlation between the temporal course of pelvic floor activation during cough.
Simultaneously, recordings of electromyographic activity of external anal sphincter (EAS EMG) and external intercostal muscle (EIC EMG) during coughing will be made with a pair of pre-gelled electrodes. Cough effort cause an involuntary pelvic contraction. Intercostals muscles recording was chosen because they are one of the muscular components of cough initiation with diaphragm muscle. 24h pad-weighing test is used to quantify urinary incontinence. We will measure the latency between the onset of the EIC EMG and the EAS EMG (RT3), during a cough effort. We will also measure the duration of the contraction, the maximum EAS EMG activity and the area under the curve.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 100 Years(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Follow in neuro-urology for lower urinary tract symptoms
- •Radical Prostatectomy
排除标准
- •Perineal Radiotherapy
- •Surgery for stress urinary incontinence
结局指标
主要结局
Latency (time)
时间窗: 1 day: During electromyographic recording
The time (latency) between the onset of the external intercostal muscle (EIC EMG) and the electromyographic activity of external anal sphincter (EAS EMG), during a cough effort.
次要结局
- Duration (time)(1 day: During electromyographic recording)
- Maximum(1 day: During electromyographic recording)
- Area under the curve(1 day: During electromyographic recording)
研究者
Gérard Amarenco
Head of Neuro-Urology department, Tenon hospital
Pierre and Marie Curie University
