Comparison of Two Approaches of Quadratus Lumborum Block for Post-operative Analgesia in Radical Cystectomy: Prospective-randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Evaluate the first call for rescue analgesia
研究概览
简要总结
To compare the postoperative analgesic effect of two ultrasound guided approaches of quadratus lumborum block (QLB) (anterior and intramuscular) for radical cystectomy.
详细描述
The quadratus lumborum block (QLB) is one of the abdominal wall block techniques used to anesthetize thoracolumbar nerves . The QLB technique was described initially by Blanco et al. in 2007 (not published), then reported initially by Kadam in 2013. Since then, QLB has evolved with the development of the ultrasound-guided nerve block. To date, several randomized controlled trials have reported effective postoperative analgesia, with non-intramuscular QLB for cesarean sections, laparoscopic gynecologic surgery and hip hemiarthroplasty .
The intramuscular QLB (QLBi) technique was first reported by. This approach is different from others in tubouchi for QLB; although the injection target sites of the other approaches are planes around the quadratus lumborum muscle, the intramuscular approach penetrates the fascia of the quadratus lumborum muscle, where local anesthetics are injected. Therefore, QLBi is relatively easier to perform compared with other QLB approaches.
The incidence of urinary bladder cancer in the Middle East and Africa is greater in areas with high rather than low SH prevalence.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age: 40-70years.
- •BMI: 20-30 kg.m2
- •Sex: both males and females.
- •American Society of Anesthesiologists (ASA )physical status: I-III.
- •Operation: radical cystectomy
排除标准
- •• Patient's refusal to participate in the study.
- •known allergy to local anesthesia (LA),
- •coagulopathy or thrombocytopenia,
- •body mass index (BMI) above 30 kg .m 2, and infection at site of injection.
- •Chronic pain syndromes,
- •Prolonged opioid medication,
- •Patients on regular use of analgesic or who received analgesic 24 h before surgery
结局指标
主要结局
Evaluate the first call for rescue analgesia
时间窗: 24hours after recovery From anesthesia
The time of the first call of analgesia is recorded
次要结局
- Total doses of morphine required(24hours after recovery from anesthesia)
研究者
Hassan mostafa abdelbaky ahmed
Comparison of Two Approaches of Quadratus Lumborum Block for Post-operative Analgesia in Radical Cystectomy
Assiut University