NCT01331902Unknown4 期
Comparison of Hyperemic Efficacy Between Nicorandil and Adenosine for Fractional Flow Reserve (FFR) Measurement
适应症
干预措施
试验速览
- 阶段
- 4 期
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Fractional Flow Reserve at Maximal Hyperemia
研究概览
简要总结
The purpose of this study is to evaluate the efficacy of nicorandil in the achievement of maximal coronary hyperemia compared with adenosine.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Diagnostic
- 盲法
- Single (Participant)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •non -infarct related, patients with moderate coronary artery stenosis
- •normal left ventricular ejection fraction on echocardiogram
排除标准
- •infarct-related arteries or clinically unstable state
- •collateral blood flow to the target vessel is shown
- •atrioventricular block on electrocardiogram
- •reduced left ventricular ejection fraction (<50%) or left ventricular hypertrophy on echocardiogram
- •contraindication of adenosine
- •bronchial asthma
研究组 & 干预措施
Adenosine Followed by Nicorandil
Experimental
干预措施: Maximal Hyperemia with Adenosine Followed by Nicorandil (Other)
Nicorandil Followed by Adenosine
Experimental
干预措施: Maximal Hyperemia with Nicorandil Followed by Adenosine (Other)
结局指标
主要结局
Fractional Flow Reserve at Maximal Hyperemia
时间窗: 1 day
次要结局
- Time to Maximal Hyperemia(1 day)
- Changes in Heart Rate(1 day)
研究者
研究点 (1)
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