NCT07000019Not yet recruitingNot Applicable
Combined Aphasia and Robot-Assisted Arm Treatment for Chronic Stroke Survivors
Conditions
Interventions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- New York Medical College
- Enrollment
- 28
- Locations
- 1
- Primary Endpoint
- Philadelphia Naming Test
Study Overview
Brief Summary
The goal of this clinical trial is to learn if a program that combines language and arm treatment can improve language and movement problems in people with chronic stroke. The mains questions it aims to answer are:
- To determine the extent to which this combined treatment can improve language.
- To determine the extent to which the combined treatment can improve arm movements.
Researchers will compare the effects of this combined treatment with treatment that targets arm movements alone.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 90 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Male or female patients between 18-90 years of age.
- •Right-handed prior to stroke
- •English-speaking (monolingual)
- •History of single left-hemisphere stroke at least 6 months prior to enrollment
- •Presence of aphasia and naming deficits on Western Aphasia Battery (WAB-R)
- •Comprehension score above 4 on WAB-R
- •Unilateral upper limb paresis (Fugl-Meyer Upper Extremity score <56)
- •Documentation of signed Informed Consent by the study participant.
Exclusion Criteria
- •Diagnosis or history of speech impairment prior to stroke
- •Severely limited speech output (score below 2 on spontaneous speech portion of WAB-R)
- •Inability to perform screening tasks due to severe language and/or cognitive impairment
- •Condition limiting passive movement in the range of motion required for robotic therapy (e.g. fixed contracture)
- •Any medical or psychiatric condition that may impact participation or compliance with study procedures or activities in the opinion of the investigator
Arms & Interventions
Combined aphasia and robot-assisted arm treatment
Experimental
Intervention: CARAT: combined aphasia and robot-assisted arm therapy (Behavioral)
Robot-assisted arm treatment
Active Comparator
Intervention: Robot-assisted arm therapy (Behavioral)
Outcomes
Primary Outcomes
Philadelphia Naming Test
Time Frame: Baseline to 1 week post-treatment
Fugl-Meyer Upper Extremity Motor Assessment
Time Frame: Baseline to 1 week post-treatment
Secondary Outcomes
- Western Aphasia Battery-Revised Aphasia Quotient(Baseline to 4 weeks post-treatment)
- Box and Blocks Test(Baseline to 1 and 4 weeks post-training)
- Apraxia Battery for Adults(Baseline to 1 and 4 weeks post-training)
- Stroke and Aphasia Quality of Life Scale-39(Baseline to 1 and 4 weeks post-training)
- Apraxia of Speech Rating Scale(Baseline to 1 and 4 weeks post-training)
Investigators
Tomoko Kitago, MD
Assistant Professor of Neurology
New York Medical College
Study Sites (1)
Loading locations...
Similar Trials
Completed
Phase 2
Efficacy of AMALS in Treating Language Impairment in ChildrenLanguage DisorderNCT00840060Lamar University40
Recruiting
Not Applicable
Combined Exercise and Targeted Therapy for Post-Stroke Reading DeficitsAphasiaStrokeReading DisorderNCT06213272Kessler Foundation70
Completed
Phase 2
Augmenting Language Therapy for Aphasia: LevodopaNonfluent AphasiaStrokeNCT01429077Shirley Ryan AbilityLab36
Completed
Not Applicable
Efficacy of a Combined Linguistic/Communication Therapy in Acute Aphasia After StrokeAphasia, AcquiredNCT03287544University Hospital, Toulouse19
Not yet recruiting
Not Applicable
Robot Mediated Therapy-Feasibility Study and Preliminary EffectsStrokeNCT05729633Changi General Hospital4