Hysterectomy with TUbectomy (HYSTUB) study

Completed

• Conditions: premature ovarian Faillure; 10029903

• Registration Number: NL-OMON40051
• Lead Sponsor: TweeSteden ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 110

Inclusion Criteria

Otherwise healthy women undergoing hysterectomy for benign indications (eg. bleeding disorder, fibroids, adenomyosis) without a family history of ovarian / tubal / breast cancer, will be asked to participate.

Exclusion Criteria

Family history of cancer, history of any form of cancer

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>concentration AMH, FSH and oestradiol pre- and six months postoperatively.<br /><br>Does a salpingectomy during hysterectomy for benign indications change hormonal<br /><br>status significantly, indicating a shift towards menopausal status?</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>What is the incidence of premalignancies in Fallopian tubes from women not at<br /><br>hereditary high risk to develop serous carcinomas? Is there a difference in<br /><br>quality of life (QoL) between the two groups?</p><br>