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Anesthesia in Flexible Bronchoscopy for Lung Cancer Diagnostic

Phase 4
Completed
Conditions
Lung Cancer
Registration Number
NCT00440960
Lead Sponsor
Hospital Pompeia
Brief Summary

The objective of the study was to establish which anesthetic procedure used during flexible bronchoscopy has the lowest index of complications.

Detailed Description

This prospective randomized study analyzed 80 patients that underwent flexible bronchoscopy. Patients were randomly assigned to four groups of 20 patients each according to the anesthetic combination used: 200 mg topical lidocaine (LID group); 200 mg topical lidocaine and 2 mg/kg propofol (PPF group); 200 mg topical lidocaine and 20 mcg/kg alfentanil (ALF group); or 200 mg topical lidocaine and 0.05 mg/kg midazolam (MID group). Scores were assigned to patients according to the different variables observed during the endoscopic procedure; the lower the score, the lower the complication index.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  • The patients included in this study were referred to FBC for the investigation of bronchial carcinoma (diagnostic procedure).
  • Patients included in the study were classified as ASA I, II and II according to the anesthetic risk classification of the American Society of Anesthesiologists (ASA).
Exclusion Criteria
  • ASA IV classification of anesthesiology risk
  • procedure that lasted longer than 15 minutes
  • indication of therapeutic bronchoscopy
  • cardiac arrhythmia and / or hypoxemia detected at admission.

Study & Design

Study Type
INTERVENTIONAL
Study Design
FACTORIAL
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (3)

Hospital Pompeia

🇧🇷

Caxias do Sul, RS, Brazil

Hospital Medianeira

🇧🇷

Caxias do Sul, RS, Brazil

General Hospital of Universidade de Caxias do Sul

🇧🇷

Caxias do Sul, RS, Brazil

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