Towards a clinical trial for oculopharyngeal muscular dystrophy (OPMD) - natural history and outcome measures.

Completed

• Conditions: oculopharyngeal muscular dystrophy; OPMD; 10029299

• Registration Number: NL-OMON42807
• Lead Sponsor: Radboud Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 80

Inclusion Criteria

- Participants of 18 years and older who have a genetically confirmed diagnosis of OPMD with or without symptoms
- Participants of 18 years and older with a clinically diagnosed OPMD, who give permission for genetic testing for OPMD

Exclusion Criteria

- Incapacitated persons will not be included in this study.
Participants can be excluded for parts of the study:
Participants with contra-indications for MRI-scan will not undergo MRI;
Participants who are claustrophobic will not undergo MRI, unless the
participant approves;
Participants who are unable to swallow, hence are dependent of non-oral
feeding or have no oral intake at all will not undergo swallowing tests.

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified