Study of Alpha-blockers Alone During Preoperative Preparation in Patients With Pheochromocytoma

Not Applicable

Completed

• Conditions: Hemodynamic; Adrenal Pheochromocytoma
• Interventions: Drug: Abandonment of intravenous volume expansion during preoperative preparation in patients with pheochromocytoma

• Registration Number: NCT05803330
• Lead Sponsor: Kunwu Yan,MM

Brief Summary

Study of the relationship between hemodynamic stability and preoperative intravenous rehydration in patients with pheochromocytoma

Detailed Description

All patients were subclassified into either the hemodynamic stability group (HS group) or the hemodynamic instability group (HU group) according to whether intraoperative hemodynamic instability occurred. Differences in data between the two groups were examined, and the risk factors for intraoperative hemodynamic instability were analyzed using logistic regression.

Study Timeline

• Study Start: 2014-02-20
• Primary Completion: 2022-10-20
• Study Completion: 2022-10-20
• Status Verified: 2023-03
• Study First Submitted: 2023-03-14
• Study First Submitted QC: 2023-03-25
• Last Update Submitted: 2023-03-25
• Study First Posted: 2023-04-07
• Last Update Posted: 2023-04-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 95

Inclusion Criteria

Clinical diagnosis of adrenal pheochromocytoma Must be able to swallow tablets

Exclusion Criteria

Bilateral or multiple pheochromocytomas. Ectopic pheochromocytoma

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
PXB group	Abandonment of intravenous volume expansion during preoperative preparation in patients with pheochromocytoma	PXB alone during preoperative preparation in patients with pheochromocytoma

Primary Outcome Measures

Name	Time	Method
intraoperative mean arterial pressure	During surgery	an intraoperative mean arterial pressure \<60 mmHg is considered to be hemodynamically unstable