Effect of combined selenium and Coenzyme Q10 on heart failure treatment

Not Applicable

• Conditions: Condition 1: Heart failure. Condition 2: Heart failure.; Congestive heart failure; Left ventricular failure

• Registration Number: IRCT2013020512371N1
• Lead Sponsor: Medical Research Department of Isfahan University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 64

Inclusion Criteria

Male and female with ischemic and nonischemic heart failure; aged between 30 to 85 years old; LVEF less than 50% (with simpson method);NYHA CLASS 2,3; stability for 1month with no change in dose and kind of drugs in at least one month perior.
Exclusion criteria: ACS or Revascularization procedure in 1month before or during study;heart failure with killip class 3, 4; active Myocarditis and pricarditis; uncontroled HTN; severe renal dysfunction (GFR less than 30%); pulmonary dysfunction( PCO2 more than 45 and Po2 less than 60); liver dysfunction(CHILD 2,3).

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
EF (Simpson). Timepoint: before intervention- after 3 month inetrvention. Method of measurement: echocardiography.;Functional calss with NYHAN CLASS. Timepoint: BEFORE INTERVENTION-3MONTH LATER. Method of measurement: questionair.

Secondary Outcome Measures

Name	Time	Method
Gastrointestinal symptoms/diarrhea. Timepoint: at the end of each mounth. Method of measurement: interview.;Echocardiography parameter (LVEF Mmode, EDD, ESD). Timepoint: after and before intervention. Method of measurement: echocardiography.;Skin rash. Timepoint: each month. Method of measurement: inteview.