Drug Compliance and Affecting Factors in Juvenile Idiopathic Arthritis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 174
- 试验地点
- 1
- 主要终点
- Disease activation score
研究概览
简要总结
The goal of this observational study is to learn about the drug compliance of patients with juvenile idiopathic arthritis and, to figure our factors that affect the compliance.
The main questions it aims to answer are:
- Medication use and compliance in children with chronic diseases is an important problem, but do patients with JIA really use their medications in harmony?
- Does the level of adherence to medications affect the quality of life of patients with JIA?
Participants will be asked to fill the demographic form which includes personal information and nutritional habbits, Morisky Drug Compliance Scale - 8 and the pediatric quality of life inventory forms, with attending researcher Yesfa Sebnem Ozbay, M.D.
This study is not an interventional study.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- — 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Being followed up with the diagnosis of Juvenile Idiopathic Artritis (JIA) from the pediatric rheumatology outpatient clinic of Istanbul University, Istanbul Faculty of Medicine
排除标准
- •Refusal of patients or their parents to participate in the study
- •Although the patient is followed up with the diagnosis of JIA, not using medication
结局指标
主要结局
Disease activation score
时间窗: November 2022 - August 2023
The activation score of the disease which will be measured by JADAS. This will help to understand the severity of the disease. JADAS consists of four items; the joint count, the physician and the patient's/parent's global assessment and the erythrocyte sedimentation rate (ESR) as an inflammatory marker. C-reactive protein (CRP) has been suggested as an alternative inflammatory marker. A higher JADAS score indicates higher disease activity as a lower JADAS score indicates lower disease activity
Drug Compliance by Morisky Medication Adherence Scale 8 (MMAS-8)
时间窗: November 2022 - August 2023
Drug adherence is a hot topic and a big issue among children and adolescents. Drug adherence among chronically ill pediatric patients will be evaluated with Morisky Medication Adherence Scale 8. With a sum of scores equalling 8, 6 to \<8, or \<6, patients can be categorized as having high, medium or low adherence to therapy, respectively.
PedsQL (Pediatric Quality of Life Inventory)
时间窗: November 2022 - August 2023
The quality of life will be evaluated by Pediatric Quality of Life Inventory (PedsQL). Items in PedsQL are reversed scored and linearly transformed to a 0-100 scale, so that higher scores indicate better quality of live. It is aimed to evaluate the quality of life scores of juvenile idiopathic arthritis patients.
次要结局
- Details of medication(November 2022 - May 2023)
- Descriptice characteristics outcome measure(November 2022 - May 2023)
研究者
Yesfa Sebnem Ozbay
M.D., Assistant Professor, Principal investigator
Istanbul University