Whipple-Rheuma Study
- Conditions
- K90.8M05M45L40.5M12.3Other intestinal malabsorptionSeropositive rheumatoid arthritisAnkylosing spondylitisArthropathic psoriasisPalindromic rheumatism
- Registration Number
- DRKS00015669
- Lead Sponsor
- DRK Krankenhaus Neuwied
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 151
Inclusion Criteria
Diagnostic criteria:; Whipple’s disease, [S2k Leitlinie Morbus Whipple, Z. Gastroenterol 2015;53:418] those with rheumatoid arthritis the 2010 American College of Rheumatology (ACR) and European League Against Rheumatism classification criteria, those with psoriasis arthritis – the CASPAR criteria, and the patients with axial spondyloarthritis – the ASAS classification criteria, Palindromic arthritis was diagnosed when episodic and saltatory arthritis with articular pain and swelling occurred in patients in the presence of either anti-citrullinated protein antibodies (ACPA) in 14 patients or isolated positive rheumatoid factor in one patient.
Exclusion Criteria
when no consent is given by the patient
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method All patients consenting and fulfilling the diagnostic criteria are asked to answer questionnaires as there were 40 patients with Whipple's disease, +20 patients with Whipple's disease as validation group + 30 patients with rheumatoid arthritis +25 patients with axial spondyloarthritis+ 21 patients with psoriatic arthritis + 15 patients with palindromic arthritis.<br>Primary outcome measure is registration and evaluation of the clinical symptoms recorded in the questionnaires.
- Secondary Outcome Measures
Name Time Method The questionnaire results studied with logistic regression analysis to check for clinical usefulness in the differential diagnosis were validated in an additional group of 20 patients with Whipple's disease