The Crosstalk Between the Epigenome and Mitochondria in SCI

Not yet recruiting

• Conditions: Injury, Spinal Cord

• Registration Number: NCT06537427
• Lead Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-8-1
• Last Update Posted: 23 September 2024

Recruitment & Eligibility

• Status: Not yet recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Inclusion Criteria:<br><br> - ASIA impairment scale grade A, B, or C upon admission;<br><br> - neurological level of injury between C1-L1;<br><br> - patient older than 18 years;<br><br> - ability to collect a valid, reliable baseline neurologic examination within 24h of<br> injury.<br><br>Exclusion Criteria:<br><br> - Concomitant TBI;<br><br> - major axial or appendicular trauma;<br><br> - in case of sedation or intoxication making unreliable the neurological examination.

Exclusion Criteria

Not provided

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes from baseline in the proteome profile in serum and CSF samples of SCI patients

Secondary Outcome Measures

Name	Time	Method
Correlation of the proteome profile of SCI patient's with their clinical profile.