Effect of Combined Use of Ivermectin and Colchicine in COVID-19 Patients

Phase 4

Completed

• Conditions: COVID-19
• Interventions: Drug: Ivermectin + colchicine; Drug: Colchicine

• Registration Number: NCT05246072
• Lead Sponsor: Ain Shams University

Brief Summary

The aim of this study will be to investigate the efficacy of use of combination of Ivermectin and colchicine on severity and outcome Of COVID 19 infection.

Detailed Description

Not available

Study Timeline

• Status Verified: 2021-10
• Study Start: 2021-11-01
• Study First Submitted: 2022-02-16
• Study First Submitted QC: 2022-02-16
• Study First Posted: 2022-02-18
• Primary Completion: 2022-02-28
• Study Completion: 2022-02-28
• Last Update Submitted: 2022-04-05
• Last Update Posted: 2022-04-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 135

Inclusion Criteria

• Willing and able to provide written informed consent prior to performing study procedures.
• Currently hospitalized and requiring medical care for non-sever COVID-19.
• One or more of the following: (positive PCR test or positive antibodies) or (CT Chest consistent with COVID19 infection).

Exclusion Criteria

• Tocilizumab use.
• Mechanical ventilation
• Requirement of oxygen supplementation >8L/min on admission

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Ivermectin + colchicine + standard care	Ivermectin + colchicine	In addition to the local standard of care for COVID 19 patients, the patient will receive: Ivermectin + Colchicine
Colchicine + standard care	Colchicine	In addition to the local standard of care for COVID 19 patients, the patient will receive: Colchicine

Primary Outcome Measures

Name	Time	Method
length of oxygen requirement	3 months

Trial Locations

Locations (1)

Ain Shams University hospitals; 🇪🇬 Cairo, Egypt