Implementation of REHACOP Cognitive Training Program in Schizophrenia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 111
- 试验地点
- 2
- 主要终点
- change in processing speed after receiving cognitive remediation
研究概览
简要总结
This study examined the efficacy of an integrative cognitive remediation program (REHACOP) to improve cognition, social cognition, clinical symptoms and functional outcome in patients with schizophrenia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnostic criteria for Schizophrenia according to American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR)
排除标准
- •evidence of alcohol or drug abuse in the last 30 days
- •previous history of significant lack of consciousness
- •mental retardation
- •relevant neurological or medical condition
结局指标
主要结局
change in processing speed after receiving cognitive remediation
时间窗: 4 months
Processing speed was assessed with Digit Symbol subtest from Wechsler Adult Intelligence Scale-III (Wechsler 1997)
Change in global functioning after receiving cognitive remediation
时间窗: 4 months
global functioning measured with Global Assessment of Functioning (GAF)
change in verbal memory after receiving cognitive remediation
时间窗: 4 months
Verbal memory performance was assessed with the Hopkins Verbal Learning Test-HVLT (Brandt and Benedict 2001)
Change in functional competence after receiving cognitive remediation
时间窗: 4 months
functional competence was measured with San Diego UCSD Performance-Based Skills Assessment- UPSA
次要结局
- change in clinical symptoms after receiving cognitive remediation(4 months)
- change in emotion perception after receiving cognitive remediation(4 months)
- change in theory of mind after receiving cognitive remediation(4 months)
- change in social perception after receiving cognitive remediation(4 months)