Implementation of REHACOP Cognitive Training Program in Schizophrenia
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Deusto
- Enrollment
- 111
- Locations
- 1
- Primary Endpoint
- change in processing speed after receiving cognitive remediation
Study Overview
Brief Summary
This study examined the efficacy of an integrative cognitive remediation program (REHACOP) to improve cognition, social cognition, clinical symptoms and functional outcome in patients with schizophrenia.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to 65 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •diagnostic criteria for Schizophrenia according to American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR)
Exclusion Criteria
- •evidence of alcohol or drug abuse in the last 30 days
- •previous history of significant lack of consciousness
- •mental retardation
- •relevant neurological or medical condition
Arms & Interventions
Rehacop group
Cognitive rehabilitation
Intervention: REHACOP (Behavioral)
Control group
Occupational activities
Intervention: Occupational activities (Behavioral)
Outcomes
Primary Outcomes
change in processing speed after receiving cognitive remediation
Time Frame: 4 months
Processing speed was assessed with Digit Symbol subtest from Wechsler Adult Intelligence Scale-III (Wechsler 1997)
Change in global functioning after receiving cognitive remediation
Time Frame: 4 months
global functioning measured with Global Assessment of Functioning (GAF)
change in verbal memory after receiving cognitive remediation
Time Frame: 4 months
Verbal memory performance was assessed with the Hopkins Verbal Learning Test-HVLT (Brandt and Benedict 2001)
Change in functional competence after receiving cognitive remediation
Time Frame: 4 months
functional competence was measured with San Diego UCSD Performance-Based Skills Assessment- UPSA
Secondary Outcomes
- change in clinical symptoms after receiving cognitive remediation(4 months)
- change in emotion perception after receiving cognitive remediation(4 months)
- change in theory of mind after receiving cognitive remediation(4 months)
- change in social perception after receiving cognitive remediation(4 months)