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临床试验/NCT05410912
NCT05410912进行中(未招募)不适用

Varicose Vein in Patients Under the Age of 40

First Affiliated Hospital of Zhejiang University1 个研究点 分布在 1 个国家目标入组 168 人开始时间: 2021年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
168
试验地点
1
主要终点
Postoperative varicose veins sequelae

研究概览

简要总结

Varicose veins are a result of valvular insufficiency and presented with twisted, enlarged veins. They not only cause cosmetic concerns but also lead to limb edema, skin pigmentation/lipodermatosclerosis, and even venous ulcers. This disease affects a large percentage of the population. Although there have been several researches on the risk factors for varicose veins and the outcomes of alternative therapies , there is currently limited data focusing on varicose veins in young patients. In this case-control study, we wanted to assess the risk factors for varicose veins in patients under the age of 40, as well as their long-term results of surgery.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • great saphenous varicose veins (GSVV) with saphenous vein reflux >0.5s.
  • lower extremity venography excluding iliac vein compression;
  • treated by great saphenous vein stripping and ambulatory phlebectomy.
  • the patient had a minimum follow-up of five years.

排除标准

  • secondary varicose veins (defined as varicose veins caused by deep vein thrombosis, iliac venous compression or venous injury etc.);
  • small saphenous veins;
  • treated by endovenous ablation/laser or sclerotherapy alone.

结局指标

主要结局

Postoperative varicose veins sequelae

时间窗: Five years after surgery.

The sequelae of the varicose vein were assessed by Venous Clinical Severity Score (VCSS). The total score is 0\~30. The higher scores mean a worse outcome.

Postoperative quality of life

时间窗: Five years after surgery.

Quality of life was assessed by the Aberdeen Varicose Vein Questionnaire (AVVQ). The total score is 1\~100. The higher scores mean a worse outcome.

次要结局

未报告次要终点

研究者

发起方
First Affiliated Hospital of Zhejiang University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Ziheng Wu, MD

Associated chief physician

First Affiliated Hospital of Zhejiang University

研究点 (1)

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