Varicose Vein in Patients Under the Age of 40
Trial Snapshot
- Phase
- Not Applicable
- Status
- Active, not recruiting
- Sponsor
- Enrollment
- 168
- Locations
- 1
- Primary Endpoint
- Postoperative varicose veins sequelae
Study Overview
Brief Summary
Varicose veins are a result of valvular insufficiency and presented with twisted, enlarged veins. They not only cause cosmetic concerns but also lead to limb edema, skin pigmentation/lipodermatosclerosis, and even venous ulcers. This disease affects a large percentage of the population. Although there have been several researches on the risk factors for varicose veins and the outcomes of alternative therapies , there is currently limited data focusing on varicose veins in young patients. In this case-control study, we wanted to assess the risk factors for varicose veins in patients under the age of 40, as well as their long-term results of surgery.
Study Design
- Study Type
- Observational
- Observational Model
- Case Control
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •great saphenous varicose veins (GSVV) with saphenous vein reflux >0.5s.
- •lower extremity venography excluding iliac vein compression;
- •treated by great saphenous vein stripping and ambulatory phlebectomy.
- •the patient had a minimum follow-up of five years.
Exclusion Criteria
- •secondary varicose veins (defined as varicose veins caused by deep vein thrombosis, iliac venous compression or venous injury etc.);
- •small saphenous veins;
- •treated by endovenous ablation/laser or sclerotherapy alone.
Outcomes
Primary Outcomes
Postoperative varicose veins sequelae
Time Frame: Five years after surgery.
The sequelae of the varicose vein were assessed by Venous Clinical Severity Score (VCSS). The total score is 0\~30. The higher scores mean a worse outcome.
Postoperative quality of life
Time Frame: Five years after surgery.
Quality of life was assessed by the Aberdeen Varicose Vein Questionnaire (AVVQ). The total score is 1\~100. The higher scores mean a worse outcome.
Secondary Outcomes
No secondary outcomes reported
Investigators
Ziheng Wu, MD
Associated chief physician
First Affiliated Hospital of Zhejiang University