Varicose Vein in Patients Under the Age of 40
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 168
- 试验地点
- 1
- 主要终点
- Postoperative varicose veins sequelae
研究概览
简要总结
Varicose veins are a result of valvular insufficiency and presented with twisted, enlarged veins. They not only cause cosmetic concerns but also lead to limb edema, skin pigmentation/lipodermatosclerosis, and even venous ulcers. This disease affects a large percentage of the population. Although there have been several researches on the risk factors for varicose veins and the outcomes of alternative therapies , there is currently limited data focusing on varicose veins in young patients. In this case-control study, we wanted to assess the risk factors for varicose veins in patients under the age of 40, as well as their long-term results of surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •great saphenous varicose veins (GSVV) with saphenous vein reflux >0.5s.
- •lower extremity venography excluding iliac vein compression;
- •treated by great saphenous vein stripping and ambulatory phlebectomy.
- •the patient had a minimum follow-up of five years.
排除标准
- •secondary varicose veins (defined as varicose veins caused by deep vein thrombosis, iliac venous compression or venous injury etc.);
- •small saphenous veins;
- •treated by endovenous ablation/laser or sclerotherapy alone.
结局指标
主要结局
Postoperative varicose veins sequelae
时间窗: Five years after surgery.
The sequelae of the varicose vein were assessed by Venous Clinical Severity Score (VCSS). The total score is 0\~30. The higher scores mean a worse outcome.
Postoperative quality of life
时间窗: Five years after surgery.
Quality of life was assessed by the Aberdeen Varicose Vein Questionnaire (AVVQ). The total score is 1\~100. The higher scores mean a worse outcome.
次要结局
未报告次要终点
研究者
Ziheng Wu, MD
Associated chief physician
First Affiliated Hospital of Zhejiang University