CTRI/2024/08/071992尚未招募不适用
Polymyxin B combined with sulbactam versus Polymyxin B combined with tigecycline in the treatment of carbapenem resistant acinetobacter baumanni pneumoniae
未提供1 个研究点 分布在 1 个国家目标入组 48 人开始时间: 2024年8月22日最近更新:
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 48
- 试验地点
- 1
- 主要终点
- ICU MORTALITY
研究概览
简要总结
There is no clear “standard of care†antibiotic regimen for CRAB infections. The current preferred approach for treating CRAB pneumonia in our intensive care unit is a combination of polymixin B with tigecycline or salbactam, depending on the physician choice. There is no data comparing the effectiveness of combination of Poymyxin B with sulbactam and Polymyxin B with Tigecyclline for CRAB pneumonia. Hence the need to conduct the study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Diagnosis of HAP or VAP.
排除标准
- •Isolation of more than one organism in respiratory specimens CRAB resistant to tigecycline and colistin Pregnant patients Patients not willing to participate in the study.
结局指标
主要结局
ICU MORTALITY
时间窗: At baseline, week 7, week 10 and week 14.
次要结局
- Length of hospital stay(Length of ICU stay)
研究者
Dr Anthur Ajay Nair
PSG Hospitals
研究点 (1)
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